Purus Labs D-Pol

Purus Labs D-pol -testosterone and nitric oxide booster all in one

Highlights of D-Pol Include:

-Increased ATP Production
-Increassed Oxygen Sparing Efficiency
-Increased Lutenizing Hormone Activation
-Increased Cirulation of Free Test

D-Pol Directions - d-pol™ contains a carefully selected blend of ingredients, based on human evidence for effect in relation to multiple aspects of health and performance. While regular and strenuous exercise, as well as optimal dietary intake inclusive of frequent, macronutrient balanced and nutrient dense meals (as well as adequate water intake) should be viewed as most important in the quest for optimal health and physical functioning, use of a dietary supplement such as d-pol™ may be an adjunct to this lifestyle plan. The use of d-pol™ should be considered in a single dosage with the largest meal of the day.

D-Pol Side Effects / Warnings - As with all nutritional supplements, potential users should only use d-pol™ under the guidance of their personal physician. Moreover, because d-aspartic acid (a chief ingredient in d-pol™) has been reported to increase circulating testosterone, d-pol™ should not be used by women. Individuals considering using d-pol™ should be healthy and over the age of 21. Users of d-pol™ should review the product nutrition panel and label for information regarding the ingredients, dosing, and precautions for use.

d-aspartic acid:
Elevating circulating testosterone has been, is now, and will likely continue to be the objective of many hard training athletes. It is well known that testosterone is associated with gains in both muscle size and strength, in addition to having positive effects on several other vital components of human health. One dietary ingredient reported to produce measureable gains in circulating testosterone is d-aspartic acid (DAA). d-aspartic acid has been reported in multiple animal and in vitro studies to be involved in testosterone synthesis, in species ranging from boar (Lamanna et al., 2007a) to lizard (Raucci et al., 2005). It also stimulates the production of other hormones such as prolactin, leutinizing hormone (LH), and growth hormone. Finally, DAA acts as a neurotransmitter/neuromodulator (D'Aniello, 2007)—an effect noted in several studies using animal models and in vitro experiments.

Considering the sound evidence for a role of DAA in testosterone synthesis, a human study was recently performed to assess the effectiveness of oral DAA supplementation with regards to testosterone elevation (Topo et al., 2009). Subjects included 43 men (27-37 yrs), 20 who received a placebo and 23 who received a DAA supplement (3.12 grams of DAA combined with B-vitamins— the same dosage of DAA provided within d-pol™). The supplement was delivered orally for 12 days. Following the 12 days of treatment with the supplement, 20 of the 23 subjects (87%) had significantly higher circulating LH levels, with an average increase of 33%. With regards to circulating testosterone, 20 of the 23 subjects (87%) had significantly higher values at day 12 compared to pretreatment, with an average increase of 42%. For both LH and testosterone, the changes were time dependent—a greater increase was observed on day 12 compared to day 6 of treatment. Therefore, it is possible that continued treatment with the supplement may have resulted in a further increase in these variables. Although measurements of muscle size and strength were not included in this study, it is possible that the increase in circulating testosterone may be associated with a measureable increase in these variables. Further work is needed to confirm these effects.

While the above findings are interesting and may prove beneficial to those seeking a natural method of increasing circulating testosterone, it should be noted that DAA has been reported to increase aromatase activity, as measured using boar testes (Lamanna et al., 2007b). At the present time it is unknown what amount of DAA would need to be orally ingested by humans in order to promote this effect. No adverse outcomes were noted in the Topo et al. (2009) investigation. Regardless, as with other testosterone stimulating agents, a cyclic schedule of supplementation of d-pol™ is recommended. If adhering to this recommendation, and when considering the inclusion of vitamin D within d-pol™, it may be wise to cycle “off” during periods of optimal sunlight exposure (when natural vitamin D synthesis would be highest—see text below for additional information pertaining to this).

B-vitamins
B-vitamins constitute an entire group of water soluble vitamins, with multiple known biochemical effects within the body—as evidenced by the thousands of scientific reports documenting such effects. B-vitamins have known effects in relation to increasing the rate of metabolism, enhancing immune function, and promoting cell growth and division. Of greatest importance in relation to the use of these vitamins within d-pol™, the B-vitamins have been used in combination with DAA for purposes of elevating circulating testosterone: B9 (folic acid), B6 (pyridoxine), and B12 (cyanocobalamin). Because dietary folic acid is not well metabolized to the active form by some individuals due to a genetic defect within the folate pathway, the naturally occurring form of this vitamin (folate) is included within d-pol™.

Nitrate
Nitrate is an inorganic anion abundant in vegetables (e.g., beets, spinach) and converted within the body to nitrite in the entero-salivary circulation (Duncan et al., 1995). The study of nitrate, nitrite, and bioactive nitrogen oxides including nitric oxide, is of great interest to investigators, due to the multiple biological roles of the nitrate-nitrite-nitric oxide pathway (Lundberg et al., 2009).